ChemMine. A Compound Mining Database for Chemical Genomics
نویسندگان
چکیده
منابع مشابه
ChemMine. A compound mining database for chemical genomics.
Chemical genomics is a promising new technology for studying gene functions in the context of living organisms or cell systems. It complements existing molecular and genetics tools (e.g. mutagenesis, RNAi) by allowing fine-tunable in vivo modulations of protein functions and cellular processes (Blackwell and Zhao, 2003; Austin et al., 2004; Lipinski and Hopkins, 2004). This approach is feasible...
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Inductive Logic Programming (ILP) is a combination of inductive learning and first-order logic aiming to learn first-order hypotheses from training examples. ILP has a serious bottleneck in an intractably enormous hypothesis search space. This makes existing approaches perform poorly on large-scale real-world datasets. In this research, we propose a technique to make the system handle an enormo...
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MOTIVATION Software applications for structural similarity searching and clustering of small molecules play an important role in drug discovery and chemical genomics. Here, we present the first open-source compound mining framework for the popular statistical programming environment R. The integration with a powerful statistical environment maximizes the flexibility, expandability and programma...
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ژورنال
عنوان ژورنال: Plant Physiology
سال: 2005
ISSN: 1532-2548,0032-0889
DOI: 10.1104/pp.105.062687